elastase-1 (LH Indholdsside)

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      <HtmlField Name="PageContent"><![CDATA[<h2>Definition</h2>
<p>&nbsp;</p>
<ul>
    <li>Koncentrationen af pancreasenzymet elastase 1 i f&aelig;ces, m&aring;lt i mikrogram per gram (&mu;g/g)&nbsp;</li>
    <li>Elastase-1 produceres i pancreas, secerneres til tarmlumen og passerer uomdannet igennem tarmkanalen. Da der er en direkte sammenh&aelig;ng mellem den duodenale sekretion fra pancreas og koncentrationen af elastase-1 i aff&oslash;ringen, er niveauet et godt udtryk for pancreas' eksokrine funktion</li>
    <li>Synomymer: Pankreaselastase 1</li>
</ul>
<h2>NPU-kode</h2>
<ul>
    <li>
    NPU28718<a href=" " data-type="journal-reference" data-value="Jahnsen J, Røseth AG, Aadland E, [Measurement of calprotectin in faeces]. Tidsskr Nor Laegeforen 2009;129: 743-5" data-value-piped="Jahnsen J, Røseth AG, Aadland E|[Measurement of calprotectin in faeces].|Tidsskr Nor Laegeforen|2009|129|743-5|19373299" data-url="reference-link" data-pubmedid="19373299" title="Jahnsen J, Røseth AG, Aadland E, [Measurement of calprotectin in faeces]. Tidsskr Nor Laegeforen 2009;129: 743-5">1</a></li>
</ul>
<h2>Navn</h2>
<ul>
    <li><strong>Langt navn</strong>
    <ul>
        <li>F&mdash;Pancreaselastase I; massefr. = ? &times; 10<sup>-6</sup></li>
    </ul>
    </li>
    <li><strong>Kort navn&nbsp;</strong>
    <ul>
        <li>Pancreaselastase I;F</li>
    </ul>
    </li>
</ul>
<h2>Referenceinterval</h2>
<ul>
    <li>Over 200 &micro;g/g</li>
</ul>
<h2>Indikationer</h2>
<ul>
    <li>Mistanke om eksokrin pancreasinsufficiens, f.eks. hos patienter med<a href="%20" title="Lindkvist B, Diagnosis and treatment of pancreatic exocrine insufficiency.  World J Gastroenterol 2013;19(42): 7258-66" data-url="reference-link" data-value-piped="Lindkvist B|Diagnosis and treatment of pancreatic exocrine insufficiency| World J Gastroenterol|2013|19(42)|7258-66" data-value="Lindkvist B, Diagnosis and treatment of pancreatic exocrine insufficiency.  World J Gastroenterol 2013;19(42): 7258-66" data-type="journal-reference">2</a><sup>,</sup><a href="%20" title="Dominici R, Franzini C, Fecal elastase-1 as a test for pancreatic function: a review. Clin Chem Lab Med 2002;40(4): 325-32" data-url="reference-link" data-value-piped="Dominici R, Franzini C|Fecal elastase-1 as a test for pancreatic function: a review|Clin Chem Lab Med|2002|40(4)|325-32" data-value="Dominici R, Franzini C, Fecal elastase-1 as a test for pancreatic function: a review. Clin Chem Lab Med 2002;40(4): 325-32" data-type="journal-reference">3</a><sup>,</sup><a href=" " data-type="journal-reference" data-value="Forsmark CE, Diagnosis and Management of Exocrine Pancreatic Insufficiency. Curr Treat Options Gastroenterol 2018;16: 306-315" data-value-piped="Forsmark CE|Diagnosis and Management of Exocrine Pancreatic Insufficiency.|Curr Treat Options Gastroenterol|2018|16|306-315|30027527" data-url="reference-link" data-pubmedid="30027527" title="Forsmark CE, Diagnosis and Management of Exocrine Pancreatic Insufficiency. Curr Treat Options Gastroenterol 2018;16: 306-315">4</a><sup>,</sup><a href=" " data-type="journal-reference" data-value="Vanga RR, Tansel A, Sidiq S, El-Serag HB, Othman MO, Diagnostic Performance of Measurement of Fecal Elastase-1 in Detection of Exocrine Pancreatic Insufficiency: Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol 2018;16: 1220-1228.e4" data-value-piped="Vanga RR, Tansel A, Sidiq S, El-Serag HB, Othman MO|Diagnostic Performance of Measurement of Fecal Elastase-1 in Detection of Exocrine Pancreatic Insufficiency: Systematic Review and Meta-analysis.|Clin Gastroenterol Hepatol|2018|16|1220-1228.e4|29374614" data-url="reference-link" data-pubmedid="29374614" title="Vanga RR, Tansel A, Sidiq S, El-Serag HB, Othman MO, Diagnostic Performance of Measurement of Fecal Elastase-1 in Detection of Exocrine Pancreatic Insufficiency: Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol 2018;16: 1220-1228.e4">5</a>
    <ul>
        <li>Ford&oslash;jelsesvanskeligheder</li>
        <li>Ern&aelig;ringsproblemer (uforklarligt v&aelig;gttab, mangelsygdomme)</li>
        <li>Kronisk diarr&eacute; eller fedtdiarr&eacute;</li>
        <li>Uforklarlige mavesmerter</li>
    </ul>
    </li>
    <li>Vurdering af pancreasfunktionen hos patienter med <a href="~/link.aspx?_id=F61E1F9A4D594FCF8DDAC06DEFC9A759&amp;_z=z">kronisk pancreatit</a> eller <a href="~/link.aspx?_id=4AF69BE2DC654560A3C10662691E6436&amp;_z=z">cystisk fibrose</a></li>
</ul>
<h2>Pr&oslash;vetagning</h2>
<ul>
    <li>Der skal anvendes 1 -5 gram f&aelig;ces (svarende til en &aelig;rt) fra et tilf&aelig;ldigt omr&aring;de af aff&oslash;ringen </li>
    <li>Pr&oslash;ven opsamles i et s&aelig;rlig pr&oslash;ver&oslash;r og sendes til laboratoriet med almindelig post </li>
    <li>Pr&oslash;ven er holdbar i 5 d&oslash;gn ved stuetemperatur</li>
</ul>
<h2>Fejlkilder</h2>
<ul>
    <li>Ved vandige diarr&eacute;er kan koncentrationen blive falsk for lav</li>
</ul>
<h2>Fortolkning</h2>
<ul>
    <li>Under 100 &mu;g/g: Sv&aelig;r pancreasinsufficiens </li>
    <li>100 - 200 &mu;g/g: Let til moderat pancreasinsufficiens</li>
</ul>
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