ferritin (LH Indholdsside)

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    <Content>
      <HtmlField Name="PageContent"><![CDATA[<h2>Definition<a href="%20" title="Ganz T, Systemic iron homeostasis. Physiol Rev 2013;93: 1721-41" data-url="reference-link" data-value="Ganz T, Systemic iron homeostasis. Physiol Rev 2013;93: 1721-41" data-type="journal-reference" data-value-piped="Ganz T|Systemic iron homeostasis|Physiol Rev|2013|93|1721-41"><sup>1</sup></a><sup>,</sup><a href=" " data-type="journal-reference" data-value="Garcia-Casal MN, Pasricha SR, Martinez RX, Lopez-Perez L, Peña-Rosas JP, Are Current Serum and Plasma Ferritin Cut-offs for Iron Deficiency and Overload Accurate and Reflecting Iron Status? A Systematic Review. Arch Med Res 2018;: " data-value-piped="Garcia-Casal MN, Pasricha SR, Martinez RX, Lopez-Perez L, Peña-Rosas JP|Are Current Serum and Plasma Ferritin Cut-offs for Iron Deficiency and Overload Accurate and Reflecting Iron Status? A Systematic Review.|Arch Med Res|2018|||30573199" data-url="reference-link" data-pubmedid="30573199" title="Garcia-Casal MN, Pasricha SR, Martinez RX, Lopez-Perez L, Peña-Rosas JP, Are Current Serum and Plasma Ferritin Cut-offs for Iron Deficiency and Overload Accurate and Reflecting Iron Status? A Systematic Review. Arch Med Res 2018;: "><sup>2</sup></a></h2>
<ul>
    <li>Ferritin er et protein i plasma, der afspejler kroppens jerndepoter </li>
    <li>Koncentrationen i plasma af ferritin m&aring;les&nbsp;som mikrogram per liter (&micro;g/L)</li>
</ul>
<h2>Synonymer</h2>
<ul>
    <li>Depot-jern&nbsp;</li>
</ul>
<h2>Indikationer</h2>
<ul>
    <li>Diagnostik af jernmangel
    <ul>
        <li>M&aring;ling af Ferritin (og CRP) og&nbsp;<a href="~/link.aspx?_id=84F24B5ECB9C48AE9BC4A1DCB7ED5C3F&amp;_z=z">P-Jern</a>&nbsp;alene er ikke altid tilstr&aelig;kkelig, da lave v&aelig;rdier ogs&aring; ses ved&nbsp;<a href="~/link.aspx?_id=F67EF4EFDACF487886702A9FA5D0F25A&amp;_z=z">an&aelig;mi ved kronisk sygdom</a>, uden at patienten har jernmangel. Dette skyldes h&oslash;jt niveau af hepcidin ved kronisk inflammation/sygdom, som blokerer for transport af jern ud af cellerne (funktionel jernmangel). </li>
        <li>Hepcidin tilbydes dog ikke rutinem&aelig;ssigt i Danmark, s&aring; videre udredning b&oslash;r tilrettel&aelig;gges ud fra kombinationen af ferritin niveau, CRP niveau og patientens klinik<a href="https://dsgh.dk/wp-content/uploads/2023/09/DSGH-Anaemi-med-Jernmangel-2023-guideline-update-sep-23.pdf" data-type="other-reference" data-value="Dansk selskab for gastroenterologi og hepatologi, guidlines: Jernmangel uden synlig blødning" data-url="https://dsgh.dk/wp-content/uploads/2023/09/DSGH-Anaemi-med-Jernmangel-2023-guideline-update-sep-23.pdf" title="Dansk selskab for gastroenterologi og hepatologi, guidlines: Jernmangel uden synlig blødning"><sup>3</sup></a><sup>,</sup><a href="https://www.sundhed.dk/sundhedsfaglig/laegehaandbogen/blod/tilstande-og-sygdomme/anaemier/jernmangelanaemi/" data-type="other-reference" data-value="Jernmangelanæmi" data-url="https://www.sundhed.dk/sundhedsfaglig/laegehaandbogen/blod/tilstande-og-sygdomme/anaemier/jernmangelanaemi/" title="Jernmangelanæmi"><sup>4</sup></a></li>
    </ul>
    </li>
    <li>Kontrol af patienter i behandling for jernmangel</li>
    <li>Diagnostik og kontrol af patienter med&nbsp;<a href="~/link.aspx?_id=DCC02894FB4B47298BC6094780800A34&amp;_z=z">h&aelig;mokromatose</a>&nbsp;og transfusionsbetinget h&aelig;mosiderose</li>
</ul>
<h2>Fortolkninger<a href="EditorPage.aspx?da=core&amp;id=%7BB347096E-158D-41C5-8AFF-F43E52829778%7D&amp;ed=FIELD548674564&amp;vs&amp;la=da&amp;fld=%7B850D32D3-55A1-49E4-9CDF-F0C88D91563C%7D&amp;so=%2Fsitecore%2Fsystem%2FSettings%2FHtml%20Editor%20Profiles%2FRich%20Text%20LHPH&amp;di=0&amp;hdl=H548674628&amp;mo&amp;pe=0&amp;fbd=1" data-type="journal-reference" data-value="Fonseca Ó, Ramos AS, Gomes LTS, Gomes MS, Moreira AC, New Perspectives on Circulating Ferritin: Its Role in Health and Disease. Molecules 2023;28: " data-value-piped="Fonseca Ó, Ramos AS, Gomes LTS, Gomes MS, Moreira AC|New Perspectives on Circulating Ferritin: Its Role in Health and Disease.|Molecules|2023|28||38067440" data-url="reference-link" data-pubmedid="38067440" title="Fonseca Ó, Ramos AS, Gomes LTS, Gomes MS, Moreira AC, New Perspectives on Circulating Ferritin: Its Role in Health and Disease. Molecules 2023;28: " style="font-size: 13px;"><sup>5</sup></a></h2>
<h3>Lave v&aelig;rdier</h3>
<ul>
    <li>V&aelig;rdier under 10-15 &micro;g/L er diagnostisk for manifest jernmangel, og er et typisk fund ved&nbsp;<a href="~/link.aspx?_id=3E0BE5773DAD45AEBB1BD38356541539&amp;_z=z">jernmangelan&aelig;mi</a><a href=" " data-type="journal-reference" data-value="Garcia-Casal MN, Pasricha SR, Martinez RX, Lopez-Perez L, Peña-Rosas JP, Are Current Serum and Plasma Ferritin Cut-offs for Iron Deficiency and Overload Accurate and Reflecting Iron Status? A Systematic Review. Arch Med Res 2018;49: 405-417" data-value-piped="Garcia-Casal MN, Pasricha SR, Martinez RX, Lopez-Perez L, Peña-Rosas JP|Are Current Serum and Plasma Ferritin Cut-offs for Iron Deficiency and Overload Accurate and Reflecting Iron Status? A Systematic Review.|Arch Med Res|2018|49|405-417|30573199" data-url="reference-link" data-pubmedid="30573199" title="Garcia-Casal MN, Pasricha SR, Martinez RX, Lopez-Perez L, Peña-Rosas JP, Are Current Serum and Plasma Ferritin Cut-offs for Iron Deficiency and Overload Accurate and Reflecting Iron Status? A Systematic Review. Arch Med Res 2018;49: 405-417"><sup>6</sup></a></li>
    <li>Der kan v&aelig;re jernmangel ved ferritin v&aelig;rdier st&oslash;rre end 15 &micro;g/L, n&aring;r patienten har andre sygdomme, se herunder</li>
    <li>V&aelig;rdier i den nedre ende af referenceintervallet er udtryk for sm&aring; jerndepoter</li>
</ul>
<h3>Normale v&aelig;rdier</h3>
<ul>
    <li>Patienter med jernmangel, som samtidig har en infektion eller en anden inflammatorisk sygdom, kan have "falsk normale v&aelig;rdier" fordi ferritin er en fasereaktant, som stiger ved b&aring;de akutte og kroniske tilstande<a href=" " data-type="journal-reference" data-value="Galloway MJ, Stuart W, Smellie A, Investigating iron status in microcytic anaemia. BMJ 2006;333: 791-3" data-value-piped="Galloway MJ, Stuart W, Smellie A|Investigating iron status in microcytic anaemia|BMJ|2006|333|791-3|17038737" data-url="reference-link" data-pubmedid="17038737" title="Galloway MJ, Stuart W, Smellie A, Investigating iron status in microcytic anaemia. BMJ 2006;333: 791-3"><sup>7</sup></a></li>
    <li>Det kan derfor anbefales altid at bestille&nbsp;<a href="~/link.aspx?_id=F10DDAF5C6D84D01874EFE1D27450A03&amp;_z=z">C-reaktivt protein (CRP)</a>&nbsp;sammen med ferritin, for bedre at kunne fortolke v&aelig;rdierne
    <ul>
        <li>Hvis CRP er normal, s&aring; betyder en normal ferritin, fx mellem 50 og 100 &micro;g/L, at patienten ikke har jernmangel</li>
        <li>Er CRP derimod klart forh&oslash;jet, udelukker en normal ferritin ikke, at patienten har jernmangel, is&aelig;r ikke hvis ferritin ligger i den lave ende af referenceintervallet
        <ul>
            <li>Man kan bruge den tommelfingerregel, at ferritin skal v&aelig;re over 100 &micro;g/L, for at man med rimelig sikkerhed kan udelukke jernmangel, ogs&aring; hos patienter med forh&oslash;jet CRP</li>
        </ul>
        </li>
    </ul>
    </li>
</ul>
<h3>Forh&oslash;jede v&aelig;rdier<a href="EditorPage.aspx?da=core&amp;id=%7BB347096E-158D-41C5-8AFF-F43E52829778%7D&amp;ed=FIELD6592443609&amp;vs&amp;la=da&amp;fld=%7B850D32D3-55A1-49E4-9CDF-F0C88D91563C%7D&amp;so=%2Fsitecore%2Fsystem%2FSettings%2FHtml%20Editor%20Profiles%2FRich%20Text%20LHPH&amp;di=0&amp;hdl=H6592443688&amp;us=sitecore%5Canvi&amp;mo&amp;pe=0&amp;fbd=1" title="Lyngbye J, Kjær A, Ladefoged SA, Nissen PH. Lyngbyes laboratoriemedicin. 2. udg. København: Nyt Nordisk Forlag Arnold Busck A/S;; 2010" data-url="reference-link" data-value="Lyngbye J, Kjær A, Ladefoged SA, Nissen PH. Lyngbyes laboratoriemedicin. 2. udg. København: Nyt Nordisk Forlag Arnold Busck A/S;; 2010" data-type="book-reference" data-value-piped="Lyngbye J, Kjær A, Ladefoged SA, Nissen PH| Lyngbyes laboratoriemedicin. 2. udg|København|Nyt Nordisk Forlag Arnold Busck A/S;|2010"><sup>8</sup></a><sup>,</sup><a href=" " data-type="journal-reference" data-value="Lorcerie B, Audia S, Samson M, Millière A, Falvo N, Leguy-Seguin V, Berthier S, Bonnotte B, Diagnosis of hyperferritinemia in routine clinical practice. Presse Med 2017;46: e329-e338" data-value-piped="Lorcerie B, Audia S, Samson M, Millière A, Falvo N, Leguy-Seguin V, Berthier S, Bonnotte B|Diagnosis of hyperferritinemia in routine clinical practice.|Presse Med|2017|46|e329-e338|29150231" data-url="reference-link" data-pubmedid="29150231" title="Lorcerie B, Audia S, Samson M, Millière A, Falvo N, Leguy-Seguin V, Berthier S, Bonnotte B, Diagnosis of hyperferritinemia in routine clinical practice. Presse Med 2017;46: e329-e338"><sup>9</sup></a></h3>
<p>Forh&oslash;jet ferritin kan dels v&aelig;re associeret med en r&aelig;kke sygdomme, samt v&aelig;re prediktivt for udvikling af en r&aelig;kke sygdomme. Man b&oslash;r dog altid afklare om der findes en underliggende infekti&oslash;s forklaring. &Aring;rsagerne til forh&oslash;jede ferritin koncentrationer kan deles i to grupper: Uden jernoverskud og med jernoverskud.</p>
<p><strong>Uden jernoverskud
</strong></p>
<ul>
    <li>Inflammation&nbsp; b&aring;de akut eller kronisk og uafh&aelig;ngigt af &aring;rsag kan f&oslash;re til forh&oslash;jede ferritin niveauer<a href="EditorPage.aspx?da=core&amp;id=%7BB347096E-158D-41C5-8AFF-F43E52829778%7D&amp;ed=FIELD6592443609&amp;vs&amp;la=da&amp;fld=%7B850D32D3-55A1-49E4-9CDF-F0C88D91563C%7D&amp;so=%2Fsitecore%2Fsystem%2FSettings%2FHtml%20Editor%20Profiles%2FRich%20Text%20LHPH&amp;di=0&amp;hdl=H6592443688&amp;us=sitecore%5Canvi&amp;mo&amp;pe=0&amp;fbd=1" data-type="journal-reference" data-value="Ueda N, Takasawa K, Impact of Inflammation on Ferritin, Hepcidin and the Management of Iron Deficiency Anemia in Chronic Kidney Disease. Nutrients 2018;10: " data-value-piped="Ueda N, Takasawa K|Impact of Inflammation on Ferritin, Hepcidin and the Management of Iron Deficiency Anemia in Chronic Kidney Disease.|Nutrients|2018|10||30150549" data-url="reference-link" data-pubmedid="30150549" title="Ueda N, Takasawa K, Impact of Inflammation on Ferritin, Hepcidin and the Management of Iron Deficiency Anemia in Chronic Kidney Disease. Nutrients 2018;10: "><sup>10</sup></a></li>
    <li>Cytolyse (lever, muskel)
    <ul>
        <li>Meget forh&oslash;jede v&aelig;rdier kan ogs&aring; ses som et forbig&aring;ende f&aelig;nomen ved akutte sygdomme med omfattende celleskader</li>
        <li>Ekstremt h&oslash;je v&aelig;rdier (over 20.000 &micro;g/L) kan ses ved sv&aelig;r toksisk leverskade og ved aggressiv virushepatit</li>
    </ul>
    </li>
    <li>Kr&aelig;ft og h&aelig;matologiske sygdomme
    <ul>
        <li>V&aelig;rdier over 1.000 &micro;g/L kan ses ved&nbsp;<a href="~/link.aspx?_id=74EC65F527604F97902B4328B39D50F3&amp;_z=z">akut myeloid leuk&aelig;mi</a></li>
        <li>H&oslash;je v&aelig;rdier kan ogs&aring; indicere onkologisk tilstand<a href="EditorPage.aspx?da=core&amp;id=%7BB347096E-158D-41C5-8AFF-F43E52829778%7D&amp;ed=FIELD548674564&amp;vs&amp;la=da&amp;fld=%7B850D32D3-55A1-49E4-9CDF-F0C88D91563C%7D&amp;so=%2Fsitecore%2Fsystem%2FSettings%2FHtml%20Editor%20Profiles%2FRich%20Text%20LHPH&amp;di=0&amp;hdl=H548674628&amp;mo&amp;pe=0&amp;fbd=1" data-type="journal-reference" data-value="Fonseca Ó, Ramos AS, Gomes LTS, Gomes MS, Moreira AC, New Perspectives on Circulating Ferritin: Its Role in Health and Disease. Molecules 2023;28: " data-value-piped="Fonseca Ó, Ramos AS, Gomes LTS, Gomes MS, Moreira AC|New Perspectives on Circulating Ferritin: Its Role in Health and Disease.|Molecules|2023|28||38067440" data-url="reference-link" data-pubmedid="38067440" title="Fonseca Ó, Ramos AS, Gomes LTS, Gomes MS, Moreira AC, New Perspectives on Circulating Ferritin: Its Role in Health and Disease. Molecules 2023;28: "><sup>5</sup></a></li>
    </ul>
    </li>
    <li>Kronisk alkoholoverforbrug</li>
    <li>Metabolisk syndrom</li>
    <li><a href="~/link.aspx?_id=6F8C67265AD4418CBB1BA4514AE6EA53&amp;_z=z">Hyperthyroidisme</a>, Type 2 diabetes Mellitus, non-alkoholisk leversygdom<a href=" " data-type="journal-reference" data-value="Makri E, Orfanidou M, Makri ES, Goulas A, Terpos E, Polyzos SA, Circulating Ferritin in Patients with Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis. J Clin Exp Hepatol 2024;14: 101353" data-value-piped="Makri E, Orfanidou M, Makri ES, Goulas A, Terpos E, Polyzos SA|Circulating Ferritin in Patients with Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis.|J Clin Exp Hepatol|2024|14|101353|38435724" data-url="reference-link" data-pubmedid="38435724" title="Makri E, Orfanidou M, Makri ES, Goulas A, Terpos E, Polyzos SA, Circulating Ferritin in Patients with Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis. J Clin Exp Hepatol 2024;14: 101353"><sup>11</sup></a>, fedme</li>
    <li><a href="~/link.aspx?_id=DCF1C3E20B9F4793BCC2A32A62103849&amp;_z=z">Gauchers sygdom</a></li>
    <li>Makrofagaktivering syndrom</li>
    <li>Stills sygdom L-ferritin, med eller uden gr&aring; st&aelig;r</li>
</ul>
<p><strong>Med jernoverskud (permanent forh&oslash;jede v&aelig;rdier, med samtidig forh&oslash;jet&nbsp;<a href="~/link.aspx?_id=5E75EFD21BC945608B6B111075CCBCD4&amp;_z=z">transferrinm&aelig;tning</a>&nbsp;(jernm&aelig;tning))</strong>
</p>
<ul>
    <li><a href="~/link.aspx?_id=DCC02894FB4B47298BC6094780800A34&amp;_z=z">H&aelig;mokromatose</a>&nbsp;(HFE-1 og mutationer i andre gener i regulationer af jernhomeostasesen)
    <ul>
        <li>Ved heredit&aelig;r h&aelig;mokromatose i tidlige stadier (f&oslash;r 25 &aring;rs alderen) findes ferritin kun let forh&oslash;jet, hvorimod&nbsp;<a href="~/link.aspx?_id=5E75EFD21BC945608B6B111075CCBCD4&amp;_z=z">transferrinm&aelig;tningen</a>&nbsp;som regel er forh&oslash;jet</li>
    </ul>
    </li>
    <li>For&oslash;get jernindtagelse eller infusioner (patienter med kronisk dialyse og h&oslash;jt niveau atleter)</li>
    <li>Gentagen transfusion</li>
    <li>Kroniske leversygdomme</li>
    <li><a href="~/link.aspx?_id=486BACB8477C4704BEB3207427A14F7D&amp;_z=z">Porphyria cutanea tarda</a></li>
    <li>Kompenseret dyserythropoiesis</li>
    <li>Metabolisk syndrom</li>
    <li>Aceruloplasminemia ses is&aelig;r ved fremskreden&nbsp;<a href="~/link.aspx?_id=DCC02894FB4B47298BC6094780800A34&amp;_z=z">h&aelig;mokromatose</a>&nbsp;og transfusionsh&aelig;mosiderose</li>
</ul>
<h3>Fortolkninger i kombination med andre variable</h3>
<ul>
    <li>Udover CRP og transferrinm&aelig;tning, som n&aelig;vnt ovenfor, kan resultater af m&aring;linger af&nbsp;<a href="~/link.aspx?_id=1C076597F5CC44009B6BCF6DB47452F2&amp;_z=z">retikulocytter</a>&nbsp;og&nbsp;<a href="~/link.aspx?_id=4E069076F34F4077947BAB18D80D3686&amp;_z=z">transferrin-receptor (TfR)</a>&nbsp;v&aelig;re informative i nogle kliniske sammenh&aelig;nge</li>
</ul>
<h2>Fejlkilder&nbsp;(og kilder til normal variation)</h2>
<ul>
    <li>Ingen tekniske, men se nedenfor vedr&oslash;rende fortolkning af v&aelig;rdierne ved samtidig forekomst af jernmangel og inflammation</li>
</ul>
<h2>Biokemisk baggrund<a href=" " data-type="journal-reference" data-value="Fonseca Ó, Ramos AS, Gomes LTS, Gomes MS, Moreira AC, New Perspectives on Circulating Ferritin: Its Role in Health and Disease. Molecules 2023;28: " data-value-piped="Fonseca Ó, Ramos AS, Gomes LTS, Gomes MS, Moreira AC|New Perspectives on Circulating Ferritin: Its Role in Health and Disease.|Molecules|2023|28||38067440" data-url="reference-link" data-pubmedid="38067440" title="Fonseca Ó, Ramos AS, Gomes LTS, Gomes MS, Moreira AC, New Perspectives on Circulating Ferritin: Its Role in Health and Disease. Molecules 2023;28: "><sup>5</sup></a></h2>
<ul>
    <li>Ferritin indeholder to forskellige subunits hhv. L-ferritin og H-ferritin og findes intracellul&aelig;rt i cytosol og mitokodrier is&aelig;r i lever, milt og knoglemarv</li>
    <li>Ferritin molekyle best&aring;r af 24 subunitis, der former et spferisk kompleks, som omgiver en krystallinsk kerne med op 3000 jernatomer og fosfat</li>
    <li>Ved behov frigives jern fra ferritin, mekanismen er ikke kendt</li>
    <li>Ferritin er kroppens vigtigste depotform for jern,&nbsp;</li>
    <li>Plasmakoncentrationen er s&aelig;dvanligvis et godt m&aring;l for kroppens samlede jerndepoter, n&aring;r det g&aelig;lder jern mangel<a href=" " data-type="journal-reference" data-value="V AK, Rao PS, Adappa S, Balanthimogru P, Mahabala C, Correlation between serum ferritin and bone marrow iron stores. Trop Doct 2017;47: 217-221" data-value-piped="V AK, Rao PS, Adappa S, Balanthimogru P, Mahabala C|Correlation between serum ferritin and bone marrow iron stores.|Trop Doct|2017|47|217-221|28689489" data-url="reference-link" data-pubmedid="28689489" title="V AK, Rao PS, Adappa S, Balanthimogru P, Mahabala C, Correlation between serum ferritin and bone marrow iron stores. Trop Doct 2017;47: 217-221"><sup>12</sup></a>&nbsp;</li>
    <li>Hvis en patient er ved at udvikle jernmangel, s&aring; er ferritin det f&oslash;rste, der begynder at falde</li>
    <li>Det er f&oslash;rst senere, at&nbsp;<a href="~/link.aspx?_id=84F24B5ECB9C48AE9BC4A1DCB7ED5C3F&amp;_z=z">jern</a>&nbsp;begynder at falde, og&nbsp;<a href="~/link.aspx?_id=5E75EFD21BC945608B6B111075CCBCD4&amp;_z=z">transferrin</a>&nbsp;at stige. H<a href="~/link.aspx?_id=1D0865567D7A4C5390DD04F060A183C4&amp;_z=z">&aelig;moglobin</a>&nbsp;falder f&oslash;rst sent i forl&oslash;bet&nbsp;</li>
    <li>N&aring;r det g&aelig;lder jern overskud b&oslash;r ferritin m&aring;lingen suppleres med yderligere unders&oslash;gelser</li>
    <li>Ferritin er ogs&aring; en fasereaktant, dvs. at plasmakoncentationen stiger ved inflammatoriske tilstande, hvilket&nbsp;kan medf&oslash;re fortolkningsm&aelig;ssige vanskeligheder&nbsp;</li>
    <li>H&oslash;jt ferritinniveau er associeret med sv&aelig;r COVID-19 infektion, og h&oslash;jere ferritin niveauer korrelerer med fatalt udkomme af COVID-19</li>
    <li>Sekretionen stimuleres af pro-inflammatoriske cytokiner og ferritin har ogs&aring; selv en pro-inflammatorisk virkning. Derved spiller ferritin ogs&aring; en rolle vedr&oslash;rende graden af den inflammatiske proces</li>
</ul>
<h2>Pr&oslash;vetagning</h2>
<ul>
    <li>Veneblodpr&oslash;ve</li>
    <li>Blod i r&oslash;r med lithium-heparin, EDTA eller uden antikoagulans (t&oslash;rglas)</li>
    <li>Afpipetteret serum eller plasma er holdbart i 1 d&oslash;gn ved stuetemperatur og i 2 d&oslash;gn ved 4<sup>o</sup>C</li>
</ul>
<h2>Referenceintervaller</h2>
<ul>
    <li>Der kan v&aelig;re forskelle i de angivne intervaller fra laboratorium til laboratorium, b&aring;de afh&aelig;ngigt af de anvendte m&aring;lemetoder og referencepopulationen</li>
    <li>Voksne
    <ul>
        <li>M&aelig;nd: 22 - 355 &micro;g/L</li>
        <li>Kvinder under 50 &aring;r: 15 - 120 &micro;g/L</li>
        <li>Kvinder over 50 &aring;r: 15 &ndash; 290 &micro;g/L</li>
    </ul>
    </li>
    <li>Gravide: Der ses j&aelig;vnt faldende v&aelig;rdier i svangerskabets forl&oslash;b, ned til omkring 5 - 45 &micro;g/L. Lave v&aelig;rdier er helt almindelige under og efter f&oslash;dslen<a href="EditorPage.aspx?da=core&amp;id=%7BB347096E-158D-41C5-8AFF-F43E52829778%7D&amp;ed=FIELD6592443609&amp;vs&amp;la=da&amp;fld=%7B850D32D3-55A1-49E4-9CDF-F0C88D91563C%7D&amp;so=%2Fsitecore%2Fsystem%2FSettings%2FHtml%20Editor%20Profiles%2FRich%20Text%20LHPH&amp;di=0&amp;hdl=H6592443688&amp;us=sitecore%5Canvi&amp;mo&amp;pe=0&amp;fbd=1" title="Klajnbard A, Szecsi PB, Colov NP, Andersen MR, Jorgensen M, Bjorngaard B, et al, Laboratory reference intervals during pregnancy, delivery and the early postpartum period. Clin Chem Lab Med 2010;48: 237-48" data-url="reference-link" data-value="Klajnbard A, Szecsi PB, Colov NP, Andersen MR, Jorgensen M, Bjorngaard B, et al, Laboratory reference intervals during pregnancy, delivery and the early postpartum period. Clin Chem Lab Med 2010;48: 237-48" data-type="journal-reference" data-value-piped="Klajnbard A, Szecsi PB, Colov NP, Andersen MR, Jorgensen M, Bjorngaard B, et al|Laboratory reference intervals during pregnancy, delivery and the early postpartum period|Clin Chem Lab Med|2010|48|237-48"><sup>13</sup></a></li>
    <li>B&oslash;rn
    <ul>
        <li>Under 4 m&aring;neder: 10 - 400 &micro;g/L</li>
        <li>4 m&aring;neder til 5 &aring;r: 10 - 80 &micro;g/L</li>
        <li>&AElig;ldre b&oslash;rn og unge: Som for voksne</li>
    </ul>
    </li>
</ul>
<h2>Patientinformation</h2>
<ul>
    <li><a href="~/link.aspx?_id=5D1DFEE1FEB1429389BF643DC8412FA8&amp;_z=z">Ferritin</a></li>
</ul>
<h2>NPU-koder og -navne</h2>
<ul>
    <li>NPU19763</li>
</ul>
<h3>Navne</h3>
<ul>
    <li><strong>Langt navn</strong>
    <ul>
        <li>P&mdash;Ferritin; massek. = ? &micro;g/L</li>
    </ul>
    </li>
    <li><strong>Kort navn</strong>
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        <li>Ferritin;P</li>
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      <HtmlField Name="Resume"><![CDATA[<h2>Resum&eacute;</h2>
<ul>
    <li>Ferritin er et intracellul&aelig;rt&nbsp;protein, der lagrer jern og dermed beskytter kroppen for skadelige effekter af jern</li>
    <li>Ferritin kan "indkapsle" op til 3000 jern atomer og udg&oslash;r kroppens st&oslash;rste depotform for jern</li>
    <li>Findes is&aelig;r i lever, milt og knoglemarv</li>
    <li>Ferritin m&aring;lt i plasma er surrogatmark&oslash;r for kroppens samlede jerndepoter, n&aring;r det g&aelig;lder jernmangel, og vil normalt v&aelig;re det f&oslash;rste tegn p&aring; jernmangel</li>
    <li>Gr&aelig;nsev&aelig;rdier for ferritin ved jernmangel afh&aelig;nger af eventuelle andre sygdomme. V&aelig;rdier mindre end 15&nbsp;&micro;g/L er dog altid diagnostisk for jernmangel og et udtryk for tomme jernlagre i knoglemarven</li>
    <li>Ferritin er ogs&aring; en akutfasereaktant. Vurdering af ferritin b&oslash;r derfor ske sammen med <a href="~/link.aspx?_id=F10DDAF5C6D84D01874EFE1D27450A03&amp;_z=z">C-reaktivt protein (CRP)</a>&nbsp;</li>
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